THZ-2-118 |CAS:1644498-54-3 Probechem Biochemicals

Chemical Structure : THZ-2-118

加入收藏

THZ-2-118 (IRAK1 inhibitor)

货号: PC-38076Not For Human Use, Lab Use Only.

THZ-2-118 is a potent selective inhibitor of IRAK1 with IC50 of 14.2 nM.

规格	价格	库存	数量
25 mg		Get quote
50 mg		Get quote
100 mg		Get quote

获取报价单

* 请选择数量再加入购物车

or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

生物&药学活性

THZ-2-118 is a potent selective inhibitor of IRAK1 with IC50 of 14.2 nM.
THZ-2-118 does not inhibitor IRAK4 at 10 uM, also potently inhibits JNK1/2/3 (IC50=1-2 nM).

物理化学性质&存储条件

分子量	493.571
分子式	C28H27N7O2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(E)-3-(4-(dimethylamino)but-2-enamido)-N-(4-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)benzamide

参考文献

1. Hatcher JM, et al. ACS Med Chem Lett. 2020 Oct 9;11(11):2238-2243.

THZ-2-118 (IRAK1 inhibitor)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

THZ-2-118 (IRAK1 inhibitor)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

Get Quotation Now

* Indicates a Required FieldYour information is safe with us.