Chemical Structure : THS-044
CAS No.: 62054-67-5
货号: PC-45660Not For Human Use, Lab Use Only.
THS-044 is a low micromolar HIF2α PAS-B binding compound (Kd=2 uM).
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THS-044 is a low micromolar HIF2α PAS-B binding compound (Kd=2 uM), modulates the affinity of the HIF2α:ARNT PAS-B heterodimer in vitro.
分子量 | 291.2265 | |
分子式 | C11H12F3N3O3 | |
外观性状 | Solid | |
储存条件 |
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Solubility |
10 mM in DMSO |
|
Chemical Name/SMILES |
4-Morpholinamine, N-[2-nitro-4-(trifluoromethyl)phenyl]- |
1. Scheuermann TH, et al. Proc Natl Acad Sci U S A. 2009 Jan 13;106(2):450-5.
2. Motto I, et al. J Chem Inf Model. 2011 Nov 28;51(11):2868-81.
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