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首页-小分子抑制剂&激动剂-Nuclear Receptor/Transcription Factor-HIF/HIF Prolyl-hydroxylase-THS-044
THS-044

Chemical Structure : THS-044

CAS No.: 62054-67-5

THS-044 (THS044;THS 044)

货号: PC-45660Not For Human Use, Lab Use Only.

THS-044 is a low micromolar HIF2α PAS-B binding compound (Kd=2 uM).

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

THS-044 is a low micromolar HIF2α PAS-B binding compound (Kd=2 uM), modulates the affinity of the HIF2α:ARNT PAS-B heterodimer in vitro.

物理化学性质&存储条件

分子量 291.2265
分子式 C11H12F3N3O3
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

4-Morpholinamine, N-[2-nitro-4-(trifluoromethyl)phenyl]-

参考文献

1. Scheuermann TH, et al. Proc Natl Acad Sci U S A. 2009 Jan 13;106(2):450-5.

2. Motto I, et al. J Chem Inf Model. 2011 Nov 28;51(11):2868-81.

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