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首页-小分子抑制剂&激动剂-Metabolic Enzyme/Protease-Aldose Reductase-TH-3021
TH-3021

Chemical Structure : TH-3021

CAS No.: 700856-05-9

TH-3021 (SN336384)

货号: PC-72285Not For Human Use, Lab Use Only.

TH-3021 (SN336384) is a potent and specific inhibitor of Aldo-keto reductase 1C3 (AKR1C3) with IC50 of 110 nM in isolated enzyme assays and 18 nM in cellular assays, displays no inhibitory action against AKR1C1/1C2/1C4 (IC50>30 uM).

规格 价格 库存 数量
25 mg Get quote
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

TH-3021 (SN336384) is a potent and specific inhibitor of Aldo-keto reductase 1C3 (AKR1C3) with IC50 of 110 nM in isolated enzyme assays and 18 nM in cellular assays, displays no inhibitory action against AKR1C1/1C2/1C4 (IC50>30 uM).

物理化学性质&存储条件

分子量 309.794
分子式 C15H20ClN3O2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(4-(4-chlorophenyl)piperazin-1-yl)(morpholino)methanone

参考文献

1. Jack U Flanagan, et al. Bioorg Med Chem. 2014 Feb 1;22(3):967-77.

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