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TH-237A

Chemical Structure : TH-237A

CAS No.: 935467-97-3

TH-237A (TH237A, meso-GS 164)

货号: PC-42798Not For Human Use, Lab Use Only.

TH-237A (meso-GS 164) is a brain penetrant neuroprotective agent that protects neurons against β-amyloid (Aβ) induced neurotoxicity.

规格 价格 库存 数量
10 mg ¥1280 In stock
25 mg ¥2180 In stock
50 mg ¥3680 In stock
100 mg Get quote

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

TH-237A (meso-GS 164) is a brain penetrant neuroprotective agent that protects neurons against β-amyloid (Aβ) induced neurotoxicity.
TH-237A increases neuronal survival in the presence of the Aβ peptides in rat isolated neuronal culture with EC50 of 5 nM.

物理化学性质&存储条件

分子量 333.3293
分子式 C18H17F2NO3
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

DMSO: ≥ 46 mg/mL

Chemical Name/SMILES

1H,3H,5H-Oxazolo[3,4-c]oxazole-7a(7H)-methanol, 3,5-bis(4-fluorophenyl)-, (3R,5S)-rel-

参考文献

1. Kelly E. Desino. Improving Blood Brain Barrier Permeation of Small Molecules Exhibiting Chemotherapeutic and Neuroprotective Effects.

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