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首页-小分子抑制剂&激动剂-Membrane Transporter/Ion Channel-TRP Channel-TH-1177
TH-1177

Chemical Structure : TH-1177

CAS No.: 300554-57-8

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TH-1177 (TH1177)

货号: PC-22128Not For Human Use, Lab Use Only.

TH-1177 is a small molecule TRPV6 calcium channel inhibitor, effectively blocks calcium entry in LNCaP prostate cancer cells and demonstrates inhibitory effects on prostate cancer proliferation.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    TH-1177 is a small molecule TRPV6 calcium channel inhibitor, effectively blocks calcium entry in LNCaP prostate cancer cells and demonstrates inhibitory effects on prostate cancer proliferation.

    物理化学性质&存储条件

    分子量 435.99
    分子式 C27H30ClNO2
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20°C 12 个月; 4°C 6 个月
    配置液
    -80°C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    (2R)-2-(((4-chlorophenyl)(phenyl)methoxy)methyl)-1-(4-methoxyphenethyl)pyrrolidine

    参考文献

    1. D M Haverstick, et al. Cancer Res. 2000 Feb 15;60(4):1002-8.

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