TGP-377/421 | miR-377 inhibitor | Probechem Biochemicals

Chemical Structure : TGP-377/421

CAS No.: 16752-89-9

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TGP-377/421 (Targapre-miR-377/421)

货号: PC-72390Not For Human Use, Lab Use Only.

TGP-377/421 (Targapre-miR-377/421) is a smalll molecule targets pre-miR-377 and inhibits its processing, binds to miR-377's Dicer processing site with Kd of 29 uM.

规格	价格	库存
5 mg	￥1380	In stock
10 mg	￥2280	In stock
25 mg	￥3880	In stock
50 mg	￥5980	In stock
100 mg		Get quote

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生物&药学活性

TGP-377/421 (Targapre-miR-377/421) is a smalll molecule targets pre-miR-377 and inhibits its processing, binds to miR-377's Dicer processing site with Kd of 29 uM.
TGP-377/421 inhibits the cellular biogenesis of miR-377 in HUVECs, reduced mature miR-377 levels in a dose-dependent fashion with IC50 of 5 uM, also inhibits miR-421.

物理化学性质&存储条件

分子量	340.39
分子式	C20H16N6
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2-(3-(6-amino-1H-benzo[d]imidazol-2-yl)phenyl)-1H-benzo[d]imidazol-5-amine

参考文献

1. Hafeez S Haniff, et al. Nat Chem. 2020 Oct;12(10):952-961.

TGP-377/421 (Targapre-miR-377/421)

生物&药学活性

物理化学性质&存储条件

参考文献

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TGP-377/421 (Targapre-miR-377/421)

生物&药学活性

物理化学性质&存储条件

参考文献

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