TFEB activator 3 | TFEB activator | Probechem Biochemicals

Chemical Structure : TFEB activator 3

CAS No.: 3027413-48-2

加入收藏

TFEB activator 3 (Compound 45)

货号: PC-28578Not For Human Use, Lab Use Only.

TFEB activator 3 is a brain penetrant small molecule activator of transcription factor EB (TFEB), promotes TFEB nuclear translocation and lysosome biogenesis by targeting the DAT-CDK9-TFEB pathway.

规格	价格	库存
5 mg	￥1280	In stock
10 mg	￥1980	In stock
25 mg	￥3480	In stock
50 mg		Get quote
100 mg		Get quote

获取报价单

* 请选择数量再加入购物车

or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

生物&药学活性

TFEB activator 3 is a brain penetrant small molecule activator of transcription factor EB (TFEB), promotes TFEB nuclear translocation and lysosome biogenesis by targeting the DAT-CDK9-TFEB pathway.
TFEB activator 3 alleviates AD-like symptoms in APP/PS1 mice by inducing lysosome biogenesis.
TFEB activator 3 reduces brain Aβ plaques and improves the memory of APP/PS1 mice.
TFEB activator 3 effectively improves learning, memory, and cognitive function in APP/PS1 mice via enhancing lysosome biogenesis and Aβ clearance.

物理化学性质&存储条件

分子量	320.39
分子式	C20H20N2O2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	5-(2-(1H-indol-3-yl)ethyl)-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinoline

参考文献

1. Jianhui Zhou, et al. J Med Chem. 2024 Jun 13;67(11):8836-8861.

TFEB activator 3 (Compound 45)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

TFEB activator 3 (Compound 45)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

Get Quotation Now

* Indicates a Required FieldYour information is safe with us.