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首页-小分子抑制剂&激动剂-Metabolic Enzyme/Protease-Adenylate Cyclase-TDI-11861
TDI-11861

Chemical Structure : TDI-11861

CAS No.: 2857049-72-8

TDI-11861 (TDI 11861)

货号: PC-49437Not For Human Use, Lab Use Only.

TDI-11861 a potent, selective second-generation soluble adenylyl cyclase (sAC, ADCY10) inhibitor with cellular IC50 of 5.5 nM.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

TDI-11861 a potent, selective second-generation soluble adenylyl cyclase (sAC, ADCY10) inhibitor with cellular IC50 of 5.5 nM.

物理化学性质&存储条件

分子量 494.928
分子式 C22H25ClF2N6O3
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(R)-(4-(2-(2-((3-(2-amino-6-chloropyrimidin-4-yl)-1-(difluoromethyl)-1H-pyrazol-4-yl)methyl)phenoxy)ethyl)morpholin-3-yl)methanol

参考文献

1. Michael Miller, et al. Journal of Medicinal Chemistry, November 8, 2022.

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