TCV-309 chloride | PAF inhibitor | Probechem Biochemicals

Chemical Structure : TCV-309 chloride

CAS No.: 121494-09-5

加入收藏

TCV-309 chloride (TCV309 chloride, TCV 309 chloride)

货号: PC-45596Not For Human Use, Lab Use Only.

TCV-309 chloride is a highly potent and selective platelet activating factor (PAF) antagonist, inhibits PAF-induced aggregation of rabbit and human platelets with IC50s of 33 nM and 55 nM respectively.

规格	价格	库存
5 mg	￥2380	In stock
10 mg	￥3780	In stock
25 mg	￥5980	In stock
50 mg		Get quote
100 mg		Get quote

获取报价单

* 请选择数量再加入购物车

or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

生物&药学活性

TCV-309 chloride is a highly potent and selective platelet activating factor (PAF) antagonist, inhibits PAF-induced aggregation of rabbit and human platelets with IC50s of 33 nM and 55 nM respectively.
TCV-309 potently protects mice from death induced by PAF and due to anaphylactic shock with ED50 of 2.1 and 2.6 ug/kg (i.v.), respectively.
TCV-309 also reverses PAF-induced hypotension and endotoxin-induced hypotension in rats.

物理化学性质&存储条件

分子量	629.9724
分子式	C30H34BrClN4O4
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	DMSO: ≥ 6.3 mg/mL
Chemical Name/SMILES	Pyridinium, 3-bromo-5-[[[3-[[2-[[(3,4-dihydro-2(1H)-isoquinolinyl)carbonyl]oxy]ethyl]amino]-3-oxopropyl]phenylamino]carbonyl]-1-propyl-, chloride (1:1)

参考文献

1. Terashita Z, et al. J Pharmacol Exp Ther. 1992 Feb;260(2):748-55.

2. Motoyama N, et al. Eur J Pain. 2013 Sep;17(8):1156-67.

3. Kuipers B, et al. J Immunol. 1994 Mar 1;152(5):2438-46.

TCV-309 chloride (TCV309 chloride, TCV 309 chloride)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

TCV-309 chloride (TCV309 chloride, TCV 309 chloride)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

Get Quotation Now

* Indicates a Required FieldYour information is safe with us.