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首页-小分子抑制剂&激动剂-JAK/STAT Signaling-Pim-TCS PIM-1 1
TCS PIM-1 1

Chemical Structure : TCS PIM-1 1

CAS No.: 491871-58-0

TCS PIM-1 1 (SC 204330;TCS PIM 1-1)

货号: PC-45414Not For Human Use, Lab Use Only.

TCS PIM-1 1 (SC 204330) is a potent, selective, ATP-competitive Pim-1 kinase inhibitor with IC50 of 50 nM; displays >400-fold selectivity over Pim-2 and MEK1/2.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

TCS PIM-1 1 (SC 204330) is a potent, selective, ATP-competitive Pim-1 kinase inhibitor with IC50 of 50 nM; displays >400-fold selectivity over Pim-2 and MEK1/2.

物理化学性质&存储条件

分子量 367.1961
分子式 C18H11BrN2O2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

DMSO: ≥ 52 mg/mL

Chemical Name/SMILES

3-Pyridinecarbonitrile, 6-(5-bromo-2-hydroxyphenyl)-1,2-dihydro-2-oxo-4-phenyl-

参考文献

1. Cheney IW, et al. Bioorg Med Chem Lett. 2007 Mar 15;17(6):1679-83.

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