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首页-小分子抑制剂&激动剂-Nuclear Receptor/Transcription Factor-Constitutive androstane receptor (CAR)-TCPOBOP
TCPOBOP

Chemical Structure : TCPOBOP

CAS No.: 76150-91-9

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TCPOBOP (CAR agonist)

货号: PC-49718Not For Human Use, Lab Use Only.

TCPOBOP is a phenobarbital-like class of CYP-inducing agent and agonist ligand for constitutive androstane receptor (CAR) with EC50 of 20 nM.

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10 mg ￥780 In stock
25 mg ￥1280 In stock
50 mg ￥1980 In stock
100 mg ￥2980 In stock
250 mg Get quote
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

TCPOBOP is a phenobarbital-like class of CYP-inducing agent and agonist ligand for constitutive androstane receptor (CAR) with EC50 of 20 nM.
TCPOBOP competes directly for occupancy of the CAR LBD.
TCPOBOP enhances CAR interaction with the coactivator SRC-1 in vivo and in vitro.

物理化学性质&存储条件

分子量 402.05
分子式 C16H8Cl4N2O2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

1,4-bis((3,5-dichloropyridin-2-yl)oxy)benzene

参考文献

1. Wei P, et al. Nature. 2000 Oct 19;407(6806):920-3.

2. Tzameli I, et al. Mol Cell Biol. 2000 May;20(9):2951-8.

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