TCP2 inhibitor 163 (Deazaflavin 163)

Chemical Structure : TCP2 inhibitor 163

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货号: PC-20288Not For Human Use, Lab Use Only.

TCP2 inhibitor 163 (Deazaflavin 163) is a potent, selective inhibitor of tyrosyl-DNA-phosphodiesterases 2 (TDP2) with EC50 of 40 nM in NPPP assays, shows selectivity against TDP1 and APE-1.

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50 mg		Get quote
100 mg		Get quote

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TCP2 inhibitor 163 (Deazaflavin 163) is a potent, selective inhibitor of tyrosyl-DNA-phosphodiesterases 2 (TDP2) with EC50 of 40 nM in NPPP assays, shows selectivity against TDP1 and APE-1.

物理化学性质&存储条件

分子量	382.34
分子式	C19H10N8O2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
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Solubility	10 mM in DMSO
Chemical Name/SMILES	10-(3-(1H-tetrazol-5-yl)phenyl)-2,4-dioxo-2,3,4,10-tetrahydropyrimido[4,5-b]quinoline-8-carbonitrile

参考文献

1. Raoof A, et al. J Med Chem. 2013 Aug 22;56(16):6352-70.