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首页-小分子抑制剂&激动剂-Membrane Transporter/Ion Channel-iGluR-TCN213
TCN213

Chemical Structure : TCN213

CAS No.: 556803-08-8

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TCN213 (TCN-213)

货号: PC-22449Not For Human Use, Lab Use Only.

TCN213 is a selective, glycine-dependently GluN2A-containing NMDARs antagonist with IC50 of 0.55 uM for GluN1/GluN2A NMDAR, negligible effect on GluN1/GluN2B NMDA receptor.

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10 mg ￥980 In stock
25 mg ￥1580 In stock
50 mg ￥2480 In stock
100 mg Get quote
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

TCN213 is a selective, glycine-dependently GluN2A-containing NMDARs antagonist with IC50 of 0.55 uM for GluN1/GluN2A NMDAR, negligible effect on GluN1/GluN2B NMDA receptor.

物理化学性质&存储条件

分子量 376.54
分子式 C18H24N4OS2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

2-((5-(Benzylamino)-1,3,4-thiadiazol-2-yl)thio)-N-(cyclohexylmethyl)acetamide

参考文献

1. McKay S, et al. Br J Pharmacol. 2012 Jun;166(3):924-37.

2. Edman S, et al. Neuropharmacology. 2012 Sep;63(3):441-9.

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