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首页-小分子抑制剂&激动剂-PI3K/Akt/mTOR Pathway-Akt-TCMDC-136364
TCMDC-136364

Chemical Structure : TCMDC-136364

CAS No.: 842148-40-7

TCMDC-136364 (AKT Kinase Inhibitor, GSK Akt inhibitor, TCMDC136364)

货号: PC-42485Not For Human Use, Lab Use Only.

TCMDC-136364 (AKT Kinase Inhibitor) is an Akt kinase inhibitor, selectively inhibits Akt in proliferating cells expressing Trop-2, also potently inhibits P. falciparum multidrug resistant strain Dd2.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

TCMDC-136364 (AKT Kinase Inhibitor) is an Akt kinase inhibitor, selectively inhibits Akt in proliferating cells expressing Trop-2, also potently inhibits P. falciparum multidrug resistant strain Dd2.

物理化学性质&存储条件

分子量 357.3672
分子式 C16H19N7O3
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

2-Propyn-1-ol, 3-[2-(4-amino-1,2,5-oxadiazol-3-yl)-7-(3-aminopropoxy)-1-ethyl-1H-imidazo[4,5-c]pyridin-4-yl]-

参考文献

1. Patent WO2013171777 A2.
2. Francisco-Javier Gamo, et al. Nature. 2010 May 20;465(7296):305-10.

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