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首页-小分子抑制剂&激动剂-Proteasome/Ubiquitin-Deubiquitinase (DUB)-TCID
TCID

Chemical Structure : TCID

CAS No.: 30675-13-9

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TCID (UCHL3 inhibitor TCID)

货号: PC-61702Not For Human Use, Lab Use Only.

TCID is a selective ubiquitin C-terminal hydrolase-L3 (UCH-L3) inhibitor with IC50 of 0.6 uM, displays >100-fold selectivity over UCH-L1.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

TCID is a selective ubiquitin C-terminal hydrolase-L3 (UCH-L3) inhibitor with IC50 of 0.6 uM, displays >100-fold selectivity over UCH-L1.
TCID diminishes glycine transporter GlyT2 ubiquitination in brain stem and spinal cord primary neurons.

物理化学性质&存储条件

分子量 283.9
分子式 C9H2Cl4O2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

4,5,6,7-Tetrachloro-1H-Indene-1,3(2H)-dione

参考文献

1. Liu Y, et al. Chem Biol. 2003 Sep;10(9):837-46.

2. de Juan-Sanz J, et al. PLoS One. 2013;8(3):e58863.

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