TC-S7009 | HIF2α inhibitor | Probechem Biochemicals

Chemical Structure : TC-S7009

CAS No.: 1422955-31-4

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TC-S7009 (TC-S 7009 )

货号: PC-22317Not For Human Use, Lab Use Only.

TC-S7009 is a specific inhibitor of HIF-2α with Kd of 81 nM, disrupts HIF-2α′s heterodimerization and DNA-binding activity, reducing the expression of HIF-2α-dependent genes.

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生物&药学活性

TC-S7009 is a specific inhibitor of HIF-2α with Kd of 81 nM, disrupts HIF-2α′s heterodimerization and DNA-binding activity, reducing the expression of HIF-2α-dependent genes.

物理化学性质&存储条件

分子量	308.65
分子式	C12H6ClFN4O3
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
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Solubility	10 mM in DMSO
Chemical Name/SMILES	N-(3-chloro-5-fluorophenyl)-4-nitrobenzo[c][1,2,5]oxadiazol-5-amine

参考文献

1. Scheuermann TH, et al. Nat Chem Biol. 2013 Apr;9(4):271-6.

TC-S7009 (TC-S 7009 )

生物&药学活性

物理化学性质&存储条件

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TC-S7009 (TC-S 7009 )

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物理化学性质&存储条件

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