TC-DAPK6 | DAPK1/3 inhibitor | Probechem Biochemicals

Chemical Structure : TC-DAPK6

CAS No.: 315694-89-4

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TC-DAPK6 (Tc-DAPK6, TC-DAPK 6)

货号: PC-22727Not For Human Use, Lab Use Only.

TC-DAPK6 is a potent, specific, ATP-competitiveinhibitor of death associated protein kinase (DAPK) with IC50 of 69 and 225 nM for DAPK1 and ZIPK (DAPK3) respectively.

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50 mg	￥1780	In stock
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生物&药学活性

TC-DAPK6 is a potent, specific, ATP-competitiveinhibitor of death associated protein kinase (DAPK) with IC50 of 69 and 225 nM for DAPK1 and ZIPK (DAPK3) respectively.
TC-DAPK6 displays selectivity for DAPK1 over a range of 48 other kinases, including Abl, AMPK, Chk1, Met and Src (IC50 > 10 μM).

物理化学性质&存储条件

分子量	276.30
分子式	C17H12N2O2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	4-(Pyridin-3-ylmethylene)-2-((E)-styryl)oxazol-5(4H)-one

参考文献

1. Zeng W, et al. Acta Biochim Biophys Sin (Shanghai). 2021 Apr 15;53(5):567-574.

2. Okamoto M, et al. J Med Chem. 2009. PMID: 19877644

TC-DAPK6 (Tc-DAPK6, TC-DAPK 6)

生物&药学活性

物理化学性质&存储条件

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TC-DAPK6 (Tc-DAPK6, TC-DAPK 6)

生物&药学活性

物理化学性质&存储条件

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