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首页-小分子抑制剂&激动剂-Nuclear Receptor/Transcription Factor-IRE1-TC-D-F07
TC-D-F07

Chemical Structure : TC-D-F07

CAS No.: 2378311-45-4

TC-D-F07

货号: PC-47076Not For Human Use, Lab Use Only.

TC-D-F07 is a novel prodrug of the covalent IRE-1 inhibitor D-F07, inhibits IRE-1/XBP-1s pathway in cancer cells.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    TC-D-F07 is a novel prodrug of the covalent IRE-1 inhibitor D-F07, inhibits IRE-1/XBP-1s pathway in cancer cells.

    物理化学性质&存储条件

    分子量 577.517
    分子式 C24H23N3O12S
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20°C 12 个月; 4°C 6 个月
    配置液
    -80°C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    7-(1,3-dioxan-2-yl)-9-methoxy-3-methyl-5-oxo-1,3,4,5-tetrahydro-2H-chromeno[3,4-c]pyridin-8-yl 2,4-dinitrobenzenesulfonate

    参考文献

    1. Andong Shao, et al. Mol Pharm. 2022 Apr 4;19(4):1059-1067.

    2. Andong Shao, et al. J Med Chem. 2019 Jun 13;62(11):5404-5413.

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