TC-5115 | MLL1 SET domain | Probechem Biochemicals

Chemical Structure : TC-5115

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TC-5115 (TC5115)

货号: PC-72008Not For Human Use, Lab Use Only.

TC-5115 (TC5115 ) is a potent, selective inhibitor of MLL1 SET domain with IC50 of 15 nM, 48 times more potent than the pan-methyltransferase inhibitor SAH.

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TC-5115 (TC5115 ) is a potent, selective inhibitor of MLL1 SET domain with IC50 of 15 nM, 48 times more potent than the pan-methyltransferase inhibitor SAH.

物理化学性质&存储条件

分子量	532.62
分子式	C23H32N8O5S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(S)-2-amino-4-((((2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl)((1-(thiophen-2-ylmethyl)azetidin-3-yl)methyl)amino)butanoic acid

参考文献

1. Chern TR, et al. ACS Med Chem Lett. 2020 May 14;11(6):1348-1352.

TC-5115 (TC5115)

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物理化学性质&存储条件

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TC-5115 (TC5115)

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