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首页-小分子抑制剂&激动剂-Antibiotics and Antivirals-Enterovirus-TBZE-029
TBZE-029

Chemical Structure : TBZE-029

CAS No.: 246148-68-5

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TBZE-029 (TBZE029)

货号: PC-62925Not For Human Use, Lab Use Only.

TBZE-029 is a selective inhibitor of the replication of several Enteroviruses with IC50 of 1.2 uM against coxsackievirus B3 replication, targets nonstructural protein 2C.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    TBZE-029 is a selective inhibitor of the replication of several Enteroviruses with IC50 of 1.2 uM against coxsackievirus B3 replication, targets nonstructural protein 2C.

    物理化学性质&存储条件

    分子量 356.314
    分子式 C16H9F5N2S
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20 °C 12 个月; 4°C 6 个月
    配置液
    -80 °C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    1-(2,6-difluorophenyl)-6-trifluoromethyl-1H,3H-thiazolo[3,4-a]benzimidazole

    参考文献

    1. De Palma AM, et al. J Virol. 2008 May;82(10):4720-30.

    2. De Palma AM, et al. Biochem Biophys Res Commun. 2007 Feb 16;353(3):628-32.

    3. Aguado L, et al. J Med Chem. 2010 Jan 14;53(1):316-24.

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