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TBC1D2 inhibitor G2

Chemical Structure : TBC1D2 inhibitor G2

CAS No.:

TBC1D2 inhibitor G2

货号: PC-27253Not For Human Use, Lab Use Only.

TBC1D2 inhibitor G2 is a small molecule TBC1 domain family member 2 (TBC1D2) inhibitor with SPR KD of 0.4 uM, and IC50 of 80 nM in HCCLM3 cells, induces selective autophagic cell death.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

TBC1D2 inhibitor G2 is a small molecule TBC1 domain family member 2 (TBC1D2) inhibitor with SPR KD of 0.4 uM, and IC50 of 80 nM in HCCLM3 cells, induces selective autophagic cell death.

物理化学性质&存储条件

分子量 590.81
分子式 C38H46N4O2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(41S,7aS,13aR,13bR,E)-11-((6-((4-(piperazin-1-ylmethyl)benzyl)oxy)naphthalen-2-yl)methylene)dodecahydro-1H,5H,10H-dipyrido[2,1-f:3',2',1'-ij][1,6]naphthyridin-10-one

参考文献

1. Han K, et al. Eur J Med Chem. 2026 Jul 4;317:119124.

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