Chemical Structure : TBBD
CAS No.: 476-66-4
货号: PC-35041Not For Human Use, Lab Use Only.
TBBD (Ellagic acid) is a specific inhibitor of coactivator-associated arginine methyltransferase 1 (CARM1, PRMT4) that selectively inhibits methylation at arginine 17 of histone H3 (H3R17).
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TBBD (Ellagic acid) is a specific inhibitor of coactivator-associated arginine methyltransferase 1 (CARM1, PRMT4) that selectively inhibits methylation at arginine 17 of histone H3 (H3R17).
TBBD shows no significant effect on the HMTase activity of G9a, as well as on the HAT activity of p300/CBP-associated factor.
分子量 | 302.194 | |
分子式 | C14H6O8 | |
外观性状 | Solid | |
储存条件 |
|
|
Solubility |
10 mM in DMSO |
|
Chemical Name/SMILES |
2,3,7,8-tetrahydroxychromeno[5,4,3-cde]chromene-5,10-dione |
1. Selvi BR, et al. J Biol Chem. 2010 Mar 5;285(10):7143-52.
2. Hatanaka Y, et al. Cell Rep. 2017 Sep 19;20(12):2756-2765.
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