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首页-小分子抑制剂&激动剂-Antibiotics and Antivirals-Bacterial-TBAJ-5307
TBAJ-5307

Chemical Structure : TBAJ-5307

CAS No.: 2583850-72-8

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TBAJ-5307 ((-)-TBAJ5307)

货号: PC-21661Not For Human Use, Lab Use Only.

TBAJ-5307 is a broad spectrum anti-non-tuberculous mycobacteria (NTM) inhibitor targeting FO-domain of F1FO-ATP synthase, shows MIC50 of 4.5 nM and 6 nM against the Mab subsp. abscessus smooth strain and rough strain respectively.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

TBAJ-5307 is a broad spectrum anti-non-tuberculous mycobacteria (NTM) inhibitor targeting FO-domain of F1FO-ATP synthase, shows MIC50 of 4.5 nM and 6 nM against the Mab subsp. abscessus smooth strain and rough strain respectively.

物理化学性质&存储条件

分子量 627.54
分子式 C30H35BrN4O6
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

(1R,2S)-1-(6-bromo-2-methoxyquinolin-3-yl)-1-(2,3-dimethoxypyridin-4-yl)-2-(2,6-dimethoxypyridin-4-yl)-4-(dimethylamino)butan-2-ol

参考文献

1. Priya Ragunathan, et al. J Biol Chem. 2024 Jan 2:105618.

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