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首页-小分子抑制剂&激动剂-Metabolic Enzyme/Protease-Protein Phosphatase/PTP-TAT-QFNP12
TAT-QFNP12

Chemical Structure : TAT-QFNP12

CAS No.:

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TAT-QFNP12

货号: PC-27322Not For Human Use, Lab Use Only.

TAT-QFNP12 is a peptide inhibitor of N-myc downstream-regulated gene 2 (NDRG2)-PPM1A interaction, blocks NDRG2-PPM1A binding and reduces Smad2/3 dephosphorylation, decreases astrocytic MMP-9 production and BBB disruption after subarachnoid hemorrhage (SAH).

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

TAT-QFNP12 is a peptide inhibitor of N-myc downstream-regulated gene 2 (NDRG2)-PPM1A interaction, blocks NDRG2-PPM1A binding and reduces Smad2/3 dephosphorylation, decreases astrocytic MMP-9 production and BBB disruption after subarachnoid hemorrhage (SAH).

物理化学性质&存储条件

分子量
分子式
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

AA Sequence: YGRKKRRQRRR-VKKEAELDKYLE

参考文献

1. Dayun Feng, et al. Sci Adv. 2022 Sep 30;8(39):eabq2423.

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