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TAT-K-tetracosapeptide

Chemical Structure : TAT-K-tetracosapeptide

CAS No.:

TAT-K-tetracosapeptide

货号: PC-72502Not For Human Use, Lab Use Only.

TAT-K-tetracosapeptide is K-tetracosapeptide fused to a cell-permeable TAT peptide, K-tetracosapeptide (K-TC) is a peptide of 24 amino acids corresponding to the helix a5 in KRAS4B, potent inhibitor of KARATE.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

TAT-K-tetracosapeptide is K-tetracosapeptide fused to a cell-permeable TAT peptide, K-tetracosapeptide (K-TC) is a peptide of 24 amino acids corresponding to the helix a5 in KRAS4B, potent inhibitor of KARATE.
TAT-K-tetracosapeptide blocks insulin-induced phosphorylation of AKT and its downstream effector TBC1D4, a Rab GTPase-activating protein.
TAT-K-tetracosapeptide strongly inhibits insulin-induced transport of GLUT4-GFP to the plasma membrane and glucose uptake in adipocytes.

物理化学性质&存储条件

分子量
分子式
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 Month
Shipping
Solubility

Chemical Name/SMILES

参考文献

1. Hiroshi Senoo, et al. Mol Cell. 2021 Nov 18;81(22):4622-4634.e8.

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