TAS2R14 agonist 28.1 | TAS2R14 agonist | Probechem Biochemicals

Chemical Structure : TAS2R14 agonist 28.1

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TAS2R14 agonist 28.1 (Cmpd28.1, Compound 28.1)

货号: PC-20067Not For Human Use, Lab Use Only.

TAS2R14 agonist 28.1 is a potent, selective agonist of bitter taste receptor TAS2R14 with EC50 of 71 nM and Emax of 129%.

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生物&药学活性

TAS2R14 agonist 28.1 is a potent, selective agonist of bitter taste receptor TAS2R14 with EC50 of 71 nM and Emax of 129%.
TAS2R14 agonist 28.1 shows a six-fold higher potency than flufenamic acid.
TAS2R14 agonist 28.1 displays marked selectivity over a panel of 24 non-bitter taste human G protein-coupled receptors.

物理化学性质&存储条件

分子量	321.27
分子式	C13H10F3N7
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N-(2-(1H-tetrazol-5-yl)phenyl)-4-methyl-6-(trifluoromethyl)pyrimidin-2-amine

参考文献

1. Lukas Waterloo, et al. J Med Chem. 2023 Feb 27. doi: 10.1021/acs.jmedchem.2c01997.

TAS2R14 agonist 28.1 (Cmpd28.1, Compound 28.1)

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物理化学性质&存储条件

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TAS2R14 agonist 28.1 (Cmpd28.1, Compound 28.1)

生物&药学活性

物理化学性质&存储条件

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