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TAS-102

Chemical Structure : TAS-102

CAS No.: 733030-01-8

TAS-102 (Trifluridine/tipiracil hydrochloride mixture)

货号: PC-27576Not For Human Use, Lab Use Only.

TAS-102 (Trifluridine/tipiracil hydrochloride mixture) is a 1:0.5 mixture of alpha,alpha,alpha-trifluorothymidine (FTD) and 5-chloro-6-[1-(2-iminopyrrolidinyl)methyl]-2,4(1H,3H)-pyrimidinedione hydrochloride thymidine phosphorylase inhibitor (TPI), inhibits thymidilate synthase (TS) and incorporation into DNA.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

TAS-102 (Trifluridine/tipiracil hydrochloride mixture) is a 1:0.5 mixture of alpha,alpha,alpha-trifluorothymidine (FTD) and 5-chloro-6-[1-(2-iminopyrrolidinyl)methyl]-2,4(1H,3H)-pyrimidinedione hydrochloride thymidine phosphorylase inhibitor (TPI), inhibits thymidilate synthase (TS) and incorporation into DNA.

物理化学性质&存储条件

分子量 435.76
分子式 C10H11F3N2O5.1/2C9H11ClN4O2.1/2HCl
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

参考文献

1. Emura T, et al. Oncol Rep. 2004 Feb;11(2):381-7.

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