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首页-小分子抑制剂&激动剂-Metabolic Enzyme/Protease-Matrix Metalloproteinase (MMP)-TAPI-1
TAPI-1

Chemical Structure : TAPI-1

CAS No.: 163847-77-6

TAPI-1

货号: PC-21092Not For Human Use, Lab Use Only.

TAPI-1 is a small molecule inhibitor of TNFalpha converting enzyme (TACE, ADAM7), blocks the shedding of several cell surface proteins.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

TAPI-1 is a small molecule inhibitor of TNFalpha converting enzyme (TACE, ADAM7), blocks the shedding of several cell surface proteins.

物理化学性质&存储条件

分子量 499.61
分子式 C26H37N5O5
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(R)-N1-((S)-1-(((S)-1-((2-Aminoethyl)amino)-1-oxopropan-2-yl)amino)-3-(naphthalen-2-yl)-1-oxopropan-2-yl)-N4-hydroxy-2-isobutylsuccinamide

参考文献

1. Bae EH, et al. Korean J Physiol Pharmacol. 2018 Mar;22(2):135-143.

2. Jolly-Tornetta C, et al. Biochemistry. 2000 Dec 12;39(49):15282-90.

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