TAOK inhibitor 43 | TAOK inhibitor | Probechem Biochemicals

Chemical Structure : TAOK inhibitor 43

CAS No.: 850467-66-2

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TAOK inhibitor 43 (TAOK-IN-1)

货号: PC-62730Not For Human Use, Lab Use Only.

TAOK inhibitor 43 (TAOK-IN-1) is a novel potent, selective, ATP-competitive TAO Kinase (TAOK) inhibitor with IC50 of 11 and 15 nM against TAOK1 and TAOK2, respectively.

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5 mg	￥580	In stock
10 mg	￥880	In stock
25 mg	￥1480	In stock
50 mg	￥2280	In stock
100 mg		Get quote

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生物&药学活性

TAOK inhibitor 43 (TAOK-IN-1) is a novel potent, selective, ATP-competitive TAO Kinase (TAOK) inhibitor with IC50 of 11 and 15 nM against TAOK1 and TAOK2, respectively.
TAOK inhibitor 43 increases the mitotic population, the percentages of mitotic cells displaying amplified centrosomes and multipolar spindles.
TAOK inhibitor 43 induces cell death, and inhibits cell growth in centrosome-amplified SKBR3 or BT549 breast cancer cell models.

物理化学性质&存储条件

分子量
分子式	C25H24N2O2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N-[2-oxo-2-(1,2,3,4-tetrahydronaphthalen-1-ylamino)ethyl]biphenyl-4-carboxamide

参考文献

1. Koo CY, et al. Mol Cancer Ther. 2017 Nov;16(11):2410-2421.

TAOK inhibitor 43 (TAOK-IN-1)

生物&药学活性

物理化学性质&存储条件

参考文献

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TAOK inhibitor 43 (TAOK-IN-1)

生物&药学活性

物理化学性质&存储条件

参考文献

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