TAK-901 |CAS:934541-31-8 Probechem Biochemicals

Chemical Structure : TAK-901

CAS No.: 934541-31-8

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TAK-901 (TAK901;TAK 901)

货号: PC-42912Not For Human Use, Lab Use Only.

TAK-901 is a multikinase inhibitor with IC50 of 21 nM and 15 nM for Aurora A/TPX2 and Aurora B/INCENP respectively.

规格	价格	库存
5 mg	￥780	In stock
10 mg	￥1180	In stock
25 mg	￥1980	In stock
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100 mg		Get quote

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生物&药学活性

TAK-901 is a multikinase inhibitor with IC50 of 21 nM and 15 nM for Aurora A/TPX2 and Aurora B/INCENP respectively.
TAK-901 inhibits 56 kinases(IC50< 100 nM).
TAK-901 inhibits kinds of cancer cell lines with EC50s of 40-500 nM.
TAK-901 suppresses cellular histone H3 phosphorylation and induced polyploidy.

物理化学性质&存储条件

分子量	504.6437
分子式	C28H32N4O3S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	9H-Pyrido[2,3-b]indole-7-carboxamide, 5-[3-(ethylsulfonyl)phenyl]-3,8-dimethyl-N-(1-methyl-4-piperidinyl)-

参考文献

1. Farrell P, et al. Mol Cancer Ther. 2013 Apr;12(4):460-70.

2. Murai S, et al. Anticancer Res. 2017 Feb;37(2):437-444.

TAK-901 (TAK901;TAK 901)

生物&药学活性

物理化学性质&存储条件

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TAK-901 (TAK901;TAK 901)

生物&药学活性

物理化学性质&存储条件

参考文献

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