Chemical Structure : TAK-448
CAS No.: 1234319-68-6
货号: PC-22641Not For Human Use, Lab Use Only.
TAK-448 (MVT-602) is a potent and full KISS1R (metastin receptor) agonist and kisspeptin analogue with IC50 of 3 pM in radioimmunoassay.
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TAK-448 (MVT-60, TAK448) is a potent and full KISS1R (metastin receptor) agonist and kisspeptin analogue with IC50 of 3 pM in radioimmunoassay.
分子量 | 1225.38 | |
分子式 | C58H80N16O14 | |
外观性状 | Solid | |
储存条件 |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
L-Tryptophanamide, N-acetyl-D-tyrosyl-(4R)-4-hydroxy-L-prolyl-L-asparaginyl-L-threonyl-L-phenylalanyl-2-azaglycyl-L-leucyl-N5-[imino(methylamino)methyl]-L-ornithyl- |
1. Yoshida N, et al. J Pharm Biomed Anal. 2012 Nov;70:369-77.
2. Matsui H, et al. Endocrinology. 2012 Nov;153(11):5297-308.
3. Matsui H, et al. Eur J Pharmacol. 2014 Jul 15;735:77-85.
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