TAF1(2) inhibitor 23 | TAF1(2) inhibitor | Probechem Biochemicals

Chemical Structure : TAF1(2) inhibitor 23

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TAF1(2) inhibitor 23 (TAF1(2) bromodomain inhibitor)

货号: PC-72707Not For Human Use, Lab Use Only.

TAF1(2) inhibitor 23 is a potent and selective TAF1(2) bromodomain inhibitor with pKi of 9.1, >5000-fold selective over BRD4(1), >50-fold selectivity over the broader bromodomains.

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TAF1(2) inhibitor 23 is a potent and selective TAF1(2) bromodomain inhibitor with pKi of 9.1, >5000-fold selective over BRD4(1), >50-fold selectivity over the broader bromodomains.

物理化学性质&存储条件

分子量	447.487
分子式	C22H27F2N5O3
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	8-((1-(3-amino-2,2-difluoropropanoyl)piperidin-4-yl)amino)-5-(3,6-dihydro-2H-pyran-4-yl)-3-methyl-1,7-naphthyridin-2(1H)-one

参考文献

1. Clegg MA, et al. ACS Med Chem Lett. 2021 Aug 3;12(8):1308-1317.

TAF1(2) inhibitor 23 (TAF1(2) bromodomain inhibitor)

生物&药学活性

物理化学性质&存储条件

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TAF1(2) inhibitor 23 (TAF1(2) bromodomain inhibitor)

生物&药学活性

物理化学性质&存储条件

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