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首页-小分子抑制剂&激动剂-Membrane Transporter/Ion Channel-SGLT-TA-1887
TA-1887

Chemical Structure : TA-1887

CAS No.: 1003005-29-5

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TA-1887 (JNJ-39933673, TA1887)

货号: PC-63415Not For Human Use, Lab Use Only.

TA-1887 (JNJ-39933673) is a potent, selective SGLT2 inhibitor with IC50 of 1.4 nM, is a novel antihyperglycemic agents through inhibition of renal SGLT2.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    TA-1887 (JNJ-39933673) is a potent, selective SGLT2 inhibitor with IC50 of 1.4 nM, is a novel antihyperglycemic agents through inhibition of renal SGLT2.

    物理化学性质&存储条件

    分子量 427.47
    分子式 C24H26FNO5
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20 °C 12 个月; 4°C 6 个月
    配置液
    -80 °C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    (2R,3R,4S,5S,6R)-2-(3-(4-cyclopropylbenzyl)-4-fluoro-1H-indol-1-yl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol

    参考文献

    1. Wang XX, et al. J Biol Chem. 2017 Mar 31;292(13):5335-5348.

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