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首页-小分子抑制剂&激动剂-Ras-Raf-MAPK-ERK Pathway-p38 MAPK-TA-02
TA-02

Chemical Structure : TA-02

CAS No.: 1784751-19-4

TA-02 (p38 MAPK inhibitor TA02)

货号: PC-42059Not For Human Use, Lab Use Only.

TA-02 is a potent p38 MAPK inhibitor with IC50 of 20 nM.

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10 mg ¥1180 In stock
25 mg ¥1980 In stock
50 mg ¥2980 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

TA-02 is a potent p38 MAPK inhibitor with IC50 of 20 nM.
TA-02 inhibits the phosphorylation of proteins downstream of p38α MAPK such as MAPKAPK2 and HSP27 during cardiogenesis, and increases ATF-2 and MEF2C during cardiac differentiation.

物理化学性质&存储条件

分子量 333.3341
分子式 C20H13F2N3
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

Pyridine, 4-[2-(2-fluorophenyl)-4-(4-fluorophenyl)-1H-imidazol-5-yl]-

参考文献

1. Laco F, et al. J Mol Cell Cardiol. 2015 Mar;80:56-70.

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