T6I-29-1A | SERM | Probechem Biochemicals

Chemical Structure : T6I-29-1A

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T6I-29-1A (Selective estrogen receptor modulator)

货号: PC-22504Not For Human Use, Lab Use Only.

T6I-29-1A is the active enantiomer of T6I-29, which is a novel isoquinoline-based selective estrogen receptor modulator (SERM), interacts with Y537S ERα ligand binding domain (LBD), exhibits anti-proliferative activities.

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生物&药学活性

物理化学性质&存储条件

分子量	514.64
分子式	C32H35FN2O3
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
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Solubility	10 mM in DMSO
Chemical Name/SMILES	(1'-(4-((1-(3-fluoropropyl)pyrrolidin-3-yl)methoxy)phenyl)-6'-hydroxy-1',4'-dihydro-2'H-spiro[cyclopropane-1,3'-isoquinolin]-2'-yl)(phenyl)methanone

参考文献

1. Young KS, et al. bioRxiv [Preprint]. 2024 Jun 2:2024.05.28.596307.

T6I-29-1A (Selective estrogen receptor modulator)

生物&药学活性

物理化学性质&存储条件

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T6I-29-1A (Selective estrogen receptor modulator)

生物&药学活性

物理化学性质&存储条件

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