Chemical Structure : T326
货号: PC-60828Not For Human Use, Lab Use Only.
T326 is a potent and selective HDAC3 inhibitor with IC50 of 0.26 uM, with no activity against HDAC1/4/6/8.
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T326 is a potent and selective HDAC3 inhibitor with IC50 of 0.26 uM, with no activity against HDAC1/4/6/8.
T326 induces dose-dependent selective increase of NF-κB acetylation in human colon cancer HCT116 cells, induces growth inhibition of cancer cells, and activates HIV gene expression in latent HIV-infected cells.
T326 shows promising activity for anticancer and antiviral benefits.
分子量 | 434.474 | |
分子式 | C21H18N6O3S | |
外观性状 | Solid | |
储存条件 |
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Solubility |
10 mM in DMSO |
1. Suzuki T, et al. PLoS One. 2013 Jul 16;8(7):e68669.
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