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首页-小分子抑制剂&激动剂-GPCR-Leukotriene Receptor-T-10430
T-10430

Chemical Structure : T-10430

CAS No.:

T-10430 (T10430)

货号: PC-23851Not For Human Use, Lab Use Only.

T-10430 is a potent and selective agonist of leukotriene B4 receptor 2 (BLT2) with EC50 of 0.51 nM in cAMP assays.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

T-10430 is a potent and selective agonist of leukotriene B4 receptor 2 (BLT2) with EC50 of 0.51 nM in cAMP assays.
T-10430 displays broad selectivity within a broad range of GPCRs, including related receptors BLT1 and AT1.
T-10430 is a chemical probe to study the consequences of BLT2 activation in vitro and in vivo.

物理化学性质&存储条件

分子量 326.40
分子式 C17H22N6O
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

1-(6-(2-(1H-Tetrazol-5-yl)phenyl)-2,6-diazaspiro[3.3]heptan-2-yl)pentan-1-one

参考文献

1. Hernandez-Olmos V, et al. J Med Chem. 2025 Jan 13. doi: 10.1021/acs.jmedchem.4c01617.

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