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首页-小分子抑制剂&激动剂-Membrane Transporter/Ion Channel-Monocarboxylate Transporter (MCT)-Syrosingopine
Syrosingopine

Chemical Structure : Syrosingopine

CAS No.: 84-36-6

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Syrosingopine (Su 3118)

货号: PC-26718Not For Human Use, Lab Use Only.

Syrosingopine (Su 3118) is an orally active lactate transporters (MCT1/MCT4) dual inhibitor, reduces glycolysis and induces synthetic lethality in cancer cells when combine with metformin.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Syrosingopine (Su 3118) is an orally active lactate transporters (MCT1/MCT4) dual inhibitor, reduces glycolysis and induces synthetic lethality in cancer cells when combine with metformin.

物理化学性质&存储条件

分子量 666.72
分子式 C35H42N2O11
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

Methyl (1S,2R,3R,4aS,13bR,14aS)-3-((4-((ethoxycarbonyl)oxy)-3,5-dimethoxybenzoyl)oxy)-2,11-dimethoxy-1,2,3,4,4a,5,7,8,13,13b,14,14a-dodecahydroindolo[2',3':3,4]pyrido[1,2-b]isoquinoline-1-carboxylate

参考文献

1. Benjamin D, et al. Cell Rep. 2018 Dec 11;25(11):3047-3058.e4.

2. Lefèvre-Borg F, et al. Hypertension. 1988 Apr;11(4):360-70.

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