Syk-IN-23 |CAS:2040321-29-5 Probechem Biochemicals

Chemical Structure : Syk-IN-23

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Syk-IN-23

货号: PC-62789Not For Human Use, Lab Use Only.

Syk-IN-23 is a potent, selective Syk kinase inhibitor with IC50 of 20 nM, possesses good PK in both rat and dog and demonstrated efficacy in rat CIA model.

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生物&药学活性

Syk-IN-23 is a potent, selective Syk kinase inhibitor with IC50 of 20 nM, possesses good PK in both rat and dog and demonstrated efficacy in rat CIA model.

物理化学性质&存储条件

分子量	474.469
分子式	C22H24F2N6O4
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	methyl (R)-(8-((4-((2,2-difluoroethyl)amino)furo[3,2-d]pyrimidin-2-yl)amino)-5,5-dimethyl-2-oxo-2,3,4,5-tetrahydro-1H-benzo[b]azepin-3-yl)carbamate

参考文献

1. Hoemann M, et al. Bioorg Med Chem Lett. 2016 Nov 15;26(22):5562-5567.

Syk-IN-23

生物&药学活性

物理化学性质&存储条件

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Syk-IN-23

生物&药学活性

物理化学性质&存储条件

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