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首页-小分子抑制剂&激动剂-GPCR-Glucagon Receptor-Survodutide
Survodutide

Chemical Structure : Survodutide

CAS No.: 2805997-46-8

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Survodutide (BI 456906, BI-456906)

货号: PC-23689Not For Human Use, Lab Use Only.

Survodutide (BI 456906) is a highly potent GCGR/GLP-1R dual agonist with EC50 of 0.52/0.60 nM respectively (human GCGR/GLP-1R), exhibits robust weight loss and glycaemic control activity.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Survodutide (BI 456906) is a highly potent GCGR/GLP-1R dual agonist with EC50 of 0.52/0.60 nM respectively (human GCGR/GLP-1R), exhibits robust weight loss and glycaemic control activity.

物理化学性质&存储条件

分子量 4231.62
分子式 C192H289N47O61
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

H-{1-amino-1-cyclobutanecarboxylic acid}-QGTFTSDYSKYLDERAAKDFIK-{GGSGSG-γE-C18 di-acid)}-WLESA-NH2

参考文献

1. Thomas L, et al. Diabetes Obes Metab. 2024 Jun;26(6):2368-2378.

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