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首页-小分子抑制剂&激动剂-Membrane Transporter/Ion Channel-Monoamine Transporter-Sulfasalazine
Sulfasalazine

Chemical Structure : Sulfasalazine

CAS No.: 599-79-1

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Sulfasalazine (NSC 667219)

货号: PC-26734Not For Human Use, Lab Use Only.

Sulfasalazine (NSC 667219) is a disease-modifying antirheumatic drug used to treat arthritis and ankylosing spondylitis, is a SLC7A11/xc(-) cystine/glutamate antiporter (xCT) inhibitor, has anti-leukemic activity against primary AML samples.

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1 g ￥380 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Sulfasalazine (NSC 667219) is a disease-modifying antirheumatic drug used to treat arthritis and ankylosing spondylitis, is a SLC7A11/xc(-) cystine/glutamate antiporter (xCT) inhibitor, has anti-leukemic activity against primary AML samples.

物理化学性质&存储条件

分子量 398.39
分子式 C18H14N4O5S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

2-Hydroxy-5-((4-(N-(pyridin-2-yl)sulfamoyl)phenyl)diazenyl)benzoic acid

参考文献

1. Nielsen OH, et al. Aliment Pharmacol Ther. 1988 Jun;2(3):203-11.

2. Berry CN, et al. Br J Pharmacol. 1988 Mar;93(3):465-72.

3. Hellewell PG, et al. Br J Pharmacol. 1982 Jun;76(2):319-26.

4. Pardieu B, et al. Leukemia. 2022 Jun;36(6):1585-1595.

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