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首页-小分子抑制剂&激动剂-Metabolic Enzyme/Protease-Protein Phosphatase/PTP-Stibogluconate sodium
Stibogluconate sodium

Chemical Structure : Stibogluconate sodium

CAS No.: 16037-91-5

Stibogluconate sodium (Sodium stibogluconate)

货号: PC-42207Not For Human Use, Lab Use Only.

Stibogluconate sodium (Sodium stibogluconate) is a multiple antimony compound that has leishmanicidal and potential antineoplastic activities, inhibits protein tyrosine phosphorylase SHP-1 (99% inhibtion at 10 ug/mL), SHP-2 and PTP1B, shows anticancer activity in synergy with IFNs.

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500 mg ¥580 In stock
1 g ¥880 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Stibogluconate sodium (Sodium stibogluconate) is a multiple antimony compound that has leishmanicidal and potential antineoplastic activities, inhibits protein tyrosine phosphorylase SHP-1 (99% inhibtion at 10 ug/mL), SHP-2 and PTP1B, shows anticancer activity in synergy with IFNs.

物理化学性质&存储条件

分子量 910.9
分子式 C12H38O26Sb2Na3
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

H2O: 550 mg/mL (Need warming); DMSO: < 9.1 mg/mL

Chemical Name/SMILES

D-Gluconic acid, 2,4:2',4'-O-(oxydistibylidyne)bis-, sodium salt, hydrate (1:3:9)

参考文献

1. Berman JD, et al. Antimicrob Agents Chemother. 1985 Jun;27(6):916-20.

2. Fan K, et al. J Immunol. 2010 Jun 1;184(11):6529-36.

3. Pathak MK, et al. J Immunol. 2001 Sep 15;167(6):3391-7.

4. Yi T, et al. J Immunol. 2002 Nov 15;169(10):5978-85.

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