Staurosporine | PKC inhibitor, Apoptosis inducer | Probechem Biochemicals

Chemical Structure : Staurosporine

CAS No.: 62996-74-1

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Staurosporine (STS, AM-2282, Antibiotic AM-2282)

货号: PC-23471Not For Human Use, Lab Use Only.

Staurosporine (STS) is a potent, ATP-competitive and non-selective inhibitor of protein kinases with IC50s of 6 nM, 15 nM, 2 nM, and 3 nM for PKC, PKA, c-Fgr, and Phosphorylase kinase respectively.

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5 mg	￥1280	In stock
10 mg	￥1980	In stock
25 mg	￥2980	In stock
50 mg	￥4880	In stock
100 mg		Get quote

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生物&药学活性

Staurosporine (STS) is a potent, ATP-competitive and non-selective inhibitor of protein kinases with IC50s of 6 nM, 15 nM, 2 nM, and 3 nM for PKC, PKA, c-Fgr, and Phosphorylase kinase respectively.
Staurosporine also inhibits TAOK2 with an IC50 of 3 μM.
Staurosporine is a classical apoptosis inducer.

物理化学性质&存储条件

分子量	466.54
分子式	C28H26N4O3
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(5S,6R,7R,9R)-6-Methoxy-5-methyl-7-(methylamino)-6,7,8,9,15,16-hexahydro-5H,14H-17-oxa-4b,9a,15-triaza-5,9-methanodibenzo[b,h]cyclonona[jkl]cyclopenta[e]-as-indacen-14-one

参考文献

1. Meggio F, et al. Eur J Biochem. 1995 Nov 15;234(1):317-22.

2. Yoshizawa S, et al. Cancer Res. 1990 Aug 15;50(16):4974-8.

3. Nabeshima T, et al. J Pharmacol Exp Ther. 1991 May;257(2):562-6.

Staurosporine (STS, AM-2282, Antibiotic AM-2282)

生物&药学活性

物理化学性质&存储条件

参考文献

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Staurosporine (STS, AM-2282, Antibiotic AM-2282)

生物&药学活性

物理化学性质&存储条件

参考文献

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