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StagX1

Chemical Structure : StagX1

CAS No.: 868224-64-0

StagX1

货号: PC-27933Not For Human Use, Lab Use Only.

StagX1 is a specific small molecule that inhibit the growth of Ewing sarcoma cells possessing mutant Stromal Antigen 2 (STAG2, SA2), selectively targets carboxylesterase 1 (CES1)-positive Ewing sarcoma cells.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

StagX1 is a specific small molecule that inhibit the growth of Ewing sarcoma cells possessing mutant Stromal Antigen 2 (STAG2, SA2), selectively targets carboxylesterase 1 (CES1)-positive Ewing sarcoma cells.

物理化学性质&存储条件

分子量 452.46
分子式 C24H24N2O7
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

ethyl 2-((2-(2-((2,3-dihydrobenzo[b][1,4]dioxin-6-yl)amino)-2-oxoethyl)-1-oxo-1,2-dihydroisoquinolin-5-yl)oxy)propanoate

参考文献

1. Zhang N, et al. ChemMedChem. 2022 May 4;17(9):e202100653.

2. Zhang N, et al. Mol Ther Oncol. 2026 Aug 11;34(3):201321.

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