Chemical Structure : Src Inhibitor 1
CAS No.: 179248-59-0
货号: PC-42303Not For Human Use, Lab Use Only.
A potent, selective dual site inhibitor of Src tyrosine kinase with Ki of 15 nM.
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
5 mg | ¥560 | In stock | |
10 mg | ¥760 | In stock | |
25 mg | ¥1760 | In stock | |
50 mg | ¥3160 | In stock |
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A potent, selective dual site inhibitor of Src tyrosine kinase with Ki of 15 nM; has IC50 of 44 nM and 88 nM for Src and Lck, respectively; shows selectivity over VEGFR2 (88-fold) and C-fms (190-fold), also inhibits Csk and Yes with similar potency as Src, no activity against p38α/p38β MAPKs or CK1δ.
分子量 | 373.40456 | |
分子式 | C22H19N3O3 | |
外观性状 | Solid | |
储存条件 |
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Solubility |
DMSO: 6.2 mg/mL (Need ultrasonic) |
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Chemical Name/SMILES |
4-Quinazolinamine, 6,7-dimethoxy-N-(4-phenoxyphenyl)- |
1. Tian G, et al. Biochemistry. 2001 Jun 19;40(24):7084-91.
2. Bain J, et al. Biochem J. 2007 Dec 15;408(3):297-315.
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