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首页-小分子抑制剂&激动剂-Cytoskeleton/Cell Adhesion Molecules-Kinesin-Sovilnesib
Sovilnesib

Chemical Structure : Sovilnesib

CAS No.: 2410796-79-9

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Sovilnesib (AMG650, AMG 650, AMG-650)

货号: PC-72904Not For Human Use, Lab Use Only.

Sovilnesib (AMG650, AMG650) is an oral, first in class, selective small molecule inhibitor of KIF18A with IC50 of 71 nM.

规格 价格 库存 数量
5 mg ￥1580 In stock
10 mg ￥2480 In stock
25 mg ￥3980 In stock
50 mg ￥5980 In stock
100 mg Get quote
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Sovilnesib (AMG650, AMG650) is an oral, first in class, selective small molecule inhibitor of KIF18A with IC50 of 71 nM.
KIF18A is a mitotic kinesin motor protein that regulates chromosome positioning during cell division and is overexpressed in a subset of human cancers.

物理化学性质&存储条件

分子量 564.653
分子式 C26H34F2N6O4S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

N-(2-(4,4-difluoropiperidin-1-yl)-6-methylpyrimidin-4-yl)-4-((2-hydroxyethyl)sulfonamido)-2-(6-azaspiro[2.5]octan-6-yl)benzamide

参考文献

1, Patent WO2021211549.

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