Solithromycin |CAS:760981-83-7 Probechem Biochemicals

Chemical Structure : Solithromycin

CAS No.: 760981-83-7

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Solithromycin (CEM-101;OP-1068)

货号: PC-45378Not For Human Use, Lab Use Only.

A novel fluoroketolide with lower MICs than those of telithromycin and macrolides.

规格	价格	库存
5 mg	￥1280	In stock
10 mg	￥2320	In stock
50 mg	￥7200	In stock

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生物&药学活性

A novel fluoroketolide with lower MICs than those of telithromycin and macrolides; binds to the large 50S subunit of the ribosome and inhibits protein biosynthesis; exhibits MICs of 7.5, 40, and 125 ng/ml for Streptococcus pneumoniae,Staphylococcus aureus, and Haemophilus influenzae, respectively.

Bacterial Infection

Approved

物理化学性质&存储条件

分子量	845.0088
分子式	C43H65FN6O10
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	DMSO: ≥ 32 mg/mL
Chemical Name/SMILES	2H-Oxacyclotetradecino[4,3-d]oxazole-2,6,8,14(1H,7H,9H)-tetrone, 1-[4-[4-(3-aminophenyl)-1H-1,2,3-triazol-1-yl]butyl]-4-ethyl-7-fluorooctahydro-11-methoxy-3a,7,9,11,13,15-hexamethyl-10-[[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy]-, (3aS,

参考文献

1. Waites KB, et al. Antimicrob Agents Chemother. 2009 May;53(5):2139-41.

2. Lemaire S, et al. Antimicrob Agents Chemother. 2009 Sep;53(9):3734-43.

3. Roblin PM, et al. Antimicrob Agents Chemother. 2010 Mar;54(3):1358-9.

Solithromycin (CEM-101;OP-1068)

生物&药学活性

物理化学性质&存储条件

参考文献

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Solithromycin (CEM-101;OP-1068)

生物&药学活性

物理化学性质&存储条件

参考文献

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