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首页-小分子抑制剂&激动剂-Metabolic Enzyme/Protease-Dipeptidyl Peptidase (DPP)-Sitagliptin phosphate
Sitagliptin phosphate

Chemical Structure : Sitagliptin phosphate

CAS No.: 654671-78-0

Sitagliptin phosphate (MK-0431, MK0431)

货号: PC-20348Not For Human Use, Lab Use Only.

Sitagliptin phosphate (MK-0431, MK0431) is a potent, orally active dipeptidyl peptidase IV (DPP4) inhibitor with IC50 of 18 nM.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Sitagliptin phosphate (MK-0431, MK0431) is a potent, orally active dipeptidyl peptidase IV (DPP4) inhibitor with IC50 of 18 nM.

物理化学性质&存储条件

分子量 505.31
分子式 C16H18F6N5O5P
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(R)-3-amino-1-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)-4-(2,4,5-trifluorophenyl)butan-1-one Phosphate

参考文献

1. Dooseop Kim, et al. J Med Chem. 2005 Jan 13;48(1):141-51.

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