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首页-小分子抑制剂&激动剂-Epigenetics-Sirtuin -SirReal1
SirReal1

Chemical Structure : SirReal1

CAS No.: 801227-82-7

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SirReal1 (SirReal 1)

货号: PC-60124Not For Human Use, Lab Use Only.

SirReal1 is novel potent, selective Sirtuin 2 (Sirt2) inhibitor with IC50 of 3.745 uM, displays no inhibitory activity against Sirt1 and Sirt 3 (IC50>100 uM).

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    SirReal1 is novel potent, selective Sirtuin 2 (Sirt2) inhibitor with IC50 of 3.745 uM, displays no inhibitory activity against Sirt1 and Sirt 3 (IC50>100 uM).

    物理化学性质&存储条件

    分子量 370.489
    分子式 C18H18N4OS2
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20 °C 12 个月; 4°C 6 个月
    配置液
    -80 °C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    N-(5-benzylthiazol-2-yl)-2-((4,6-dimethylpyrimidin-2-yl)thio)acetamide

    参考文献

    1. Schiedel M, et al. Angew Chem Int Ed Engl. 2016 Feb 5;55(6):2252-6.

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