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首页-小分子抑制剂&激动剂-Epigenetics-Sirtuin -SirReal1.1
SirReal1.1

Chemical Structure : SirReal1.1

CAS No.: 1862238-00-3

SirReal1.1 (SirReal 1.1)

货号: PC-21305Not For Human Use, Lab Use Only.

SirReal1.1 is a potent, selective inhibitor of Sirtuin 2 (Sirt2) with IC50 of 0.16 uM.

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50 mg Get quote
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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

SirReal1.1 is a potent, selective inhibitor of Sirtuin 2 (Sirt2) with IC50 of 0.16 uM.

物理化学性质&存储条件

分子量 557.69
分子式 C28H27N7O2S2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

N-(5-(3-((1-benzyl-1H-1,2,3-triazol-4-yl)methoxy)benzyl)thiazol-2-yl)-2-((4,6-dimethylpyrimidin-2-yl)thio)acetamide

参考文献

1. Matthias Schiedel, et al. Angew Chem Int Ed Engl. 2016 Feb 5;55(6):2252-6.

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